Voruciclib hydrochloride is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9 , the transcriptional regulator of MCL-1 . Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) .
Specification: ≥99%
PubChem CID: 67409218
Isomeric SMILES: CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=C(C=C(C=C4)C(F)(F)F)Cl)O)O.Cl
- UPC:
- 51413209
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- V1283123-5mg
- Product Size:
- 5mg
- CAS:
- 1000023-05-1