Biochem/physiol Actions Vosoritide is a more stable analogue of human C-type natriuretic peptide (CNP). Vosoritide binds to the Natriuretic-Peptide Receptor B (NPR B), which leads to MAPK pathway inhibition and an increased production of
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Vosoritide is a more stable analogue of human C-type natriuretic peptide (CNP). Vosoritide binds to the Natriuretic-Peptide Receptor B (NPR B), which leads to MAPK pathway inhibition and an increased production of Extracellular Matrix. It reduces the achondroplastic phenotype. Vosoritide is approved for treatment of Achondroplasia aged 5 and up.
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