WNK1-IN-1 is a selective inhibitor of WNK1 with an IC 50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC 50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancerIn VitroWNK1-IN-1 (0-1000 μM; 30 min) shows high potency to WNK1 with an IC 50 value of 1.6 μM. WNK1-IN-1 (0.2-12.5 μM; 24 h) inhibits endogenous OSR1 phosphorylation with an IC 50 value of 4.3 μM in MDAMB231 breast-cancer cells. WNK1-IN-1 (0-100 mM) is 10-fold more potent to WNK1 than WNK3 in Kinase-Glo assay. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 1.6 μM (WNK1), 4.3 μM (OSR1 phosphorylation). Specification: 0.99 Molecular Formula: C13H15BrCl2N2O4S Molecular Weight: 446.14
- UPC:
- 51432405
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- W650966-10mg
- CAS:
- 324022-39-1
- Product Size:
- 10mg
