YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis.Appearance:SolidIn Vitro:YL-939 (0.01-10 μM) efficiently protects cells from ferroptosis with IC 50 values of 0.14 μM, 0.25 μM, 0.16 μM, 0.16 μM and 0.24 μM for HT-1080, Miapaca-2, Calu-1, HCT116 and SHSY5Y cells, respectively. YL-939 (5 μM; 10 h; ES-2 cells) reduces the levIn Vivo:YL-939 (3mg/kg; i.p.; single injection) ameliorates liver damage in an Acetaminophen (APAP)-induced acute liver injury model. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: AcetaminophenBiological Activity:YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis. Specification: 0.98 Molecular Formula: C25H26N6O Molecular Weight: 426.51
- UPC:
- 51131521
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Y658768-25mg
- Product Size:
- 25mg
