Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone

Catalog No.: C15-1223-867
Manufacturer No.: C1230-1MG
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: MG

Price: $910.29

List Price: $1,011.43

Amino Acid Sequence Z-Ile-Glu-OMe-Thr-Asp-OMe-FMK Application Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) has been used as a caspase-8 inhibitor: to study the activity of caspase-8 in porcine kidney cells to study its effects on

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Description
Specifications

Amino Acid Sequence

Z-Ile-Glu-OMe-Thr-Asp-OMe-FMK

Application

Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) has been used as a caspase-8 inhibitor:

to study the activity of caspase-8 in porcine kidney cells
to study its effects on porcine parvovirus (PPV)-induced caspase-3 activity in steroidogenic luteal cells
to study its effects on retinal ganglion and astroglia in rat eyes

Biochem/physiol Actions

Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) is an irreversible and cell-permeable caspase-8 inhibitor.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:: 51303406
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: C1230-1MG

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