N-CBZ-PHE-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE (C005B-058136)

Catalog No.: C005B-058136
Mfr. No.: C9521-100MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 100
UOM: MG

Price: $3,380.62

List Price: $3,756.24

Z-Phe-Arg 7-amido-4-methylcoumarin (Z-FR-AMC) is a peptidomimetic substrate for papain and other enzymes such as cathepsin K. It is also a fluorogenic synthetic peptide for the enzymes cathepsins L and B.

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Description
Specifications

General description

Z-Phe-Arg 7-amido-4-methylcoumarin (Z-FR-AMC) is a peptidomimetic substrate for papainand other enzymes such as cathepsin K. It is also a fluorogenic synthetic peptide for the enzymes cathepsins L and B.

Application

Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride has been used:

as a fluorogenic substrate in actinidin inhibition assay
as a kallikrein substrate
as a trypsin substrate for fluorometric assay
as a cathepsin-L substrate

Biochem/physiol Actions

Z-Phe-Arg 7-amido-4-methylcoumarin (Z-FR-AMC) proteolytic lysis by proteases leads to the liberation of AMC resulting in increased fluorescence in the enzymatic reaction.

Substrates

A fluorogenic substrate for plasma kallikrein.

UPC:: 51144008
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: C9521-100MG
CAS:: 70382-26-2

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