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zatebradine hydrochloride (c15-1682-306)

ZATEBRADINE HYDROCHLORIDE (C005B-272980)

Catalog No.
C005B-272980
Mfr. No.
Z0127-10MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
10
UOM
MG
Price: $548.83
List Price: $609.81

Application Zatebradine hydrochloride has been used: as an I f blocker to study its effects on cardiomyocyte clusters (CMCs) as a hyperpolarization-activated and cyclic nucleotide-gated (HCN) channel inhibitor to study its effects on

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Application

Zatebradine hydrochloride has been used:

  • as an If blocker to study its effects on cardiomyocyte clusters (CMCs)
  • as a hyperpolarization-activated and cyclic nucleotide-gated (HCN) channel inhibitor to study its effects on viability of degenerating rod or cone photoreceptors in mice
  • as a bradycardiac agent to study its effects on tachycardia and elevated temperature in fish

Biochem/physiol Actions

Zatebradine is a bradycardiac agent.

HCN channel blocker: blocker of neuronal Ih, related cardiac If channels and ATP-sensitive Kir channels.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

UPC:
51362008
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
Z0127-10MG
CAS:
91940-87-3

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