General description
Material is complexed with up to 1 equivalent of ZnCl2
Zinc difluoromethanesulfinate is a reagent widely used to incorporate difluoromethyl functionality onto biologically significant structural motifs. It is used to difluoromethylate compounds such as heteroarenes, thiols, enones, and α, βâ€unsaturated carboxylic acids.
Application
Zinc difluoromethanesulfinate (DFMS) is part of a zinc sulfinate toolbox developed by Phil Baran for the simple and rapid diversification of heterocycles.â€
Practical and Innate Carbon-Hydrogen Functionalization of Heterocycles
DFMS is a new reagent for direct difluoromethylation of organic substrates via a radical process. This mild, operationally simple, chemoselective, and scalable difluoromethylation method is compatible with a range of nitrogen-containing heteroarene substrates of varying complexity as well as select classes of conjugated p−systems and thiols.â€
A New Reagent for Direct Difluoromethylation
Learn More at the Professor and Product Portal of Professor Phil S. Baran.
Linkage
Frequently Asked Questions are available for this Product.
- UPC:
- 51472303
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 767840-100G