(6-AMINOHEXYL)TRIPHENYLPHOSPHONIUM BROMIDE HYDROBROMIDE=95% (C005B-236101)

Application

Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This aminohexane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria.

Other Notes

Development of organelle-targetable europium complex probes for time-gated luminescence imaging of hypochlorous acid in live cells and animals

Targeting lipophilic cations to mitochondria

Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers

Molecular Weight: 442.37 (free base basis). Empirical Formula: C₂₄H₂₉BrNP · xHBr. Assay: ≥. 95%. form: solid. reaction suitability: reagent type: ligand. functional group: phosphine. storage temp.: 2-8°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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UPC:

12142207

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

GR

MPN:

905283-1G

Temperature Control Device:

Yes