Application
(±)-AMPA has been used:
- whole-cell patch-clamp recording in Müller glial cells
- to test its excitotoxic effects in hippocampal slice cultures
- in retinal horizontal cells (HCs) culture to test its effect on Ca2+ signals
Biochem/physiol Actions
Potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.
Molecular Weight: 186.17. Empirical Formula: C7H10N2O4. form: solid. color: white. solubility: H2O: 1 . mg/mL (warm), 0.1 M HCl: 3.5 . mg/mL, 0.1 M NaOH: 4.3 . mg/mL, DMSO: 4.3 . mg/mL, 1 M HCl: 50 . mg/mL. SMILES string: O.Cc1onc(O)c1CC(N)C(O): O. InChI: 1S/C7H10N2O4.H2O/c1-3-4(6(10)9-13-3)2-5(8)7(11)12. /h5H,2,8H2,1H3,(H,9,10)(H,11,12). 1H2. InChI key: HFISYNCCKQHIAM-UHFFFAOYSA-N. Gene Information: rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Slc1a1(25550), Slc1a2(29482), Slc1a3(29483). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).- UPC:
- 41121807
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A6816-10MG