(+-)-A-AMINO-3-HYDROXY-5-METHYL- ISOXAZOLE-4-PROPIONIC ACID HYDRATE (C005B-239228)

Application

(±)-AMPA has been used:

• in vivo

• whole-cell patch-clamp recording in Mller glial cells
• to test its excitotoxic effects in hippocampal slice cultures
• in retinal horizontal cells (HCs) culture to test its effect on Ca²⁺ signals

Biochem/physiol Actions

Potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.

Molecular Weight: 186.17. Empirical Formula: C₇H₁₀N₂O₄. form: solid. color: white. solubility: H₂O: 1 . mg/mL (warm), 0.1 M HCl: 3.5 . mg/mL, 0.1 M NaOH: 4.3 . mg/mL, DMSO: 4.3 . mg/mL, 1 M HCl: 50 . mg/mL. SMILES string: O.Cc1onc(O)c1CC(N)C(O): O. InChI: 1S/C7H10N2O4.H2O/c1-3-4(6(10)9-13-3)2-5(8)7(11)12. /h5H,2,8H2,1H3,(H,9,10)(H,11,12). 1H2. InChI key: HFISYNCCKQHIAM-UHFFFAOYSA-N. Gene Information: rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Slc1a1(25550), Slc1a2(29482), Slc1a3(29483). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).

UPC:

51142430

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

MG

MPN:

A6816-5MG