(+)-ETOMOXIR SODIUM SALT HYDRATE (C005B-082056)

General description

(+)-Etomoxir sodium salt hydrate belongs to oxirane carboxylic acid group of compounds and mediates metabolic channeling of fatty acid precursors. It favors oxidative stress in T cells and prevents T cell differentiation. It inhibits fatty acid oxidation and promotes hunger and food intake. Etomoxir impairs myeloid-derived suppressor cells mediated tumor and could have potential therapeutic potential.

Application

(+)-Etomoxir sodium salt hydrate has been used as an inhibitor of carnitine palmitoyltransferase 1 (CPT-1) in breast tumor cell lines and mice tumor. It has also been used as an inhibitor of fatty acid oxidation in human primary prostate epithelial cells and lymphocytes.

Biochem/physiol Actions

Irreversible O-carnitine palmitoyltransferase-1 (CPT-1) inhibitor; PPARα activator

Packaging

Store tightly sealed, protected from exposure to light

Shipping Information:

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UPC:

51142430

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes

Quantity:

5

Unit of Measurement:

MG

MPN:

E1905-5MG

CAS:

828934-41-4