10074-G5 (C007B-173921)

A c-Myc Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4, specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM) most likely due to the fact that 10074-G5 binds to a different region of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions. Specification: 10mM in DMSO Molecular Formula: C18H12N4O3 Molecular Weight: 332.31 PubChem CID: 2836600 Isomeric SMILES: C1=CC=C(C=C1)C2=CC=CC=C2NC3=CC=C(C4=NON=C34)[N+](=O)[O-] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/G423876-SCI_eec8cd317020ebc0618ac1bc7c54e3f7.pdf

UPC:

51152062

Condition:

New

Weight:

0.85 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

G423876-1ml

CAS:

413611-93-5

Product Size:

1ml

Hazard Statement Codes:

H301:H315:H319:H335

Precautionary Statement Codes:

P261:P264:P270:P271:P280