()12-HEPE-25 g

(±)12-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (±)12-HEPE is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC₅₀ values of 24 and 25 µM, respectively. These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC₅₀s = 8.6-8.8 µM).

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UPC:

51132101

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes"

WeightUOM:

LB

MPN:

32540-25

Model Number:

C790M90

Temperature Control Device:

Yes