1G244 (C005B-310976)

Biochem/physiol Actions

1G244 is a cell penetrant, highly potent and specific inhibitor of dipeptidyl peptidase 8 (DPP8) and DPP9. 1G244 is a slow-tight binding competitive inhibitor of DPP8, but it is a competitive and reversible inhibitor of DPP9.

1G244 is known to exhibit in vitro anti-myeloma actions. It might be involved in inducing pyroptotic cell death without ASC (apoptosis-associated speck-like protein containing a CARD) or interleukin (IL)-1 cleavage in human macrophage-like cells.

UPC:

12352200

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

25

Unit of Measurement:

MG

MPN:

SML2247-25MG

CAS:

847928-32-9