2-CHLORO-2'-DEOXYADENOSINE 1PC X 10MG

General description

A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. Also induces apoptosis in chronic lymphocytic leukemia (CLL) cells.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Antileukemic and immunosuppressive activity

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Other Notes

Bellosillo, B., et al. 1997. Blood 89, 3378; Bryson, H.M., and Sorkin, E.M. 1993. Drugs 46, 872.
Robertson, L.E., et al. 1993. Blood81, 143.
Carson, D.A., et al. 1988. Adv. Enzyme Regul. 27, 395.
Carson, D.A., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 2232.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Shipping Information:

Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.

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UPC:

51111741

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes

Quantity:

10

Unit of Measurement:

MG

MPN:

220467-10MG

CAS:

4291-63-8