CAYMAN CHEMICAL
3,5-dimethyl PIT-1-5 mg
A selective nonphosphoinositide inhibitor with favorable solubility in vivo that specifically disrupts PIP3/Akt PH domain binding (IC50 = 27 &muM) suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces
A selective nonphosphoinositide inhibitor with favorable solubility in vivo that specifically disrupts PIP3/Akt PH domain binding (IC50 = 27 μM); suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 36 μM).
Specifications
- UPC:
- 51262006
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10727-5
- CAS:
- 701947-53-7
- Controlled Substances and Cyanide:
- Yes



