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CAYMAN CHEMICAL

3,5-dimethyl PIT-1-5 mg

A selective nonphosphoinositide inhibitor with favorable solubility in vivo that specifically disrupts PIP3/Akt PH domain binding (IC50 = 27 &muM) suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces

Description
A selective nonphosphoinositide inhibitor with favorable solubility in vivo that specifically disrupts PIP3/Akt PH domain binding (IC50 = 27 μM); suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 36 μM).
Specifications
UPC:
51262006
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
10727-5
CAS:
701947-53-7
Controlled Substances and Cyanide:
Yes
Catalog No. C003B-377365
Price: $393.20
List Price: $436.89
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