CAYMAN CHEMICAL
3-Deazaneplanocin A-1 mg
An inhibitor of SAH hydrolase depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 &muM) increases expression of the cell-cycle regulators p21, p27, and
Description
An inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 μM); increases expression of the cell-cycle regulators p21, p27, and FBXO32 leading to cell cycle arrest and apoptosis.
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Specifications
- UPC:
- 51111631
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No"
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 13828-1
- Model Number:
- C830G17
- Temperature Control Device:
- Yes
- CAS:
- 102052-95-9
Catalog No.
C003B-120649
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