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Sigma-Aldrich

4-BROMO-1-BUTYNE 97%

4-Bromo-1-butyne is commonly used as a reactant. It serves as a source of alkyl halides for the introduction of bromo functionality into the molecule.

Description

General description

4-Bromo-1-butyne is commonly used as a reactant. It serves as a source of alkyl halides for the introduction of bromo functionality into the molecule.

Application

4-Bromo-1-butyne is used as a reactant in the synthesis of:

  • Macrocycles by cobalt-mediated [2+2+2] co-cyclotrimerization.
  • 2,4,5-trisubstituted oxazoles by a gold-catalyzed formal [3+2] cycloaddition.
  • Intramolecular 1,3-dipolar cycloaddition to synthesize 1,3,4-oxadiazoles.
  • Lactones bearing alkynes for reductive cyclization in the preparation of azulene derivatives.
  • Substituted α-pyrones by gold-catalyzed coupling reactions.

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Specifications
UPC:
51284048
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
5
Unit of Measurement:
GR
MPN:
675725-5G
CAS:
38771-21-0
Catalog No. C005B-038035
Price: $236.56
List Price: $262.84
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