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4-(dimethylamino)pyridine (c15-1205-382)

4-(Dimethylamino)pyridine (C15-1205-382)

Catalog No.
C15-1205-382
Manufacturer No.
107700-100G
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
GR
Price: $297.21
List Price: $330.24

4-(Dimethylamino)pyridine is a highly versatile nucleophilic catalyst for acylation reactions and esterifications. It is also employed in various organic transformations like Baylis-Hillman reaction, Dakin-West reaction, protection of amines,

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General description

4-(Dimethylamino)pyridine is a highly versatile nucleophilic catalyst for acylation reactions and esterifications. It is also employed in various organic transformations like Baylis-Hillman reaction, Dakin-West reaction, protection of amines, C-acylations, silylations, applications in natural products chemistry, and many others.

Application

4-(Dimethylamino)pyridine can be used as a catalyst:

  • To synthesize 3,5-disubstituted 2,6-dicyanoaniline by reacting malononitrile, aldehydes, and β-nitroolefins.
  • For the acylation of alcohols with acid anhydrides under auxiliary base- and solvent-free conditions to synthesize corresponding esters.
  • In Baylis-Hillman reaction to form carbon-carbon bond by the coupling of an activated alkene with an aldehyde or ketone.

A highly efficient catalyst for acylation reactions

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

UPC:
51473400
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
107700-100G


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