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Sigma-Aldrich

4-(Dimethylamino)pyridine, ReagentPlusr, Greater Than or Equ

4-(Dimethylamino)pyridine is a highly versatile nucleophilic catalyst for acylation reactions and esterifications. It is also employed in various organic transformations like Baylis-Hillman reaction, Dakin-West reaction, protection of amines,

Description

General description

4-(Dimethylamino)pyridine is a highly versatile nucleophilic catalyst for acylation reactions and esterifications. It is also employed in various organic transformations like Baylis-Hillman reaction, Dakin-West reaction, protection of amines, C-acylations, silylations, applications in natural products chemistry, and many others.

Application

4-(Dimethylamino)pyridine can be used as a catalyst:

  • To synthesize 3,5-disubstituted 2,6-dicyanoaniline by reacting malononitrile, aldehydes, and β-nitroolefins.
  • For the acylation of alcohols with acid anhydrides under auxiliary base- and solvent-free conditions to synthesize corresponding esters.
  • In Baylis-Hillman reaction to form carbon-carbon bond by the coupling of an activated alkene with an aldehyde or ketone.

A highly efficient catalyst for acylation reactions

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Specifications
UPC:
12352200
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
5
Unit of Measurement:
GR
MPN:
107700-5G
CAS:
1122-58-3
Temperature Control Device:
Yes
Catalog No. C005B-009008
Price: $72.00
List Price: $80.00
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  • Shipping Lead-Time: 3-5 Days
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