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Sigma-Aldrich

4-NITROPHENYL CHLOROFORMATE 96% (C005B-078739)

4-Nitrophenyl chloroformate, also known as p-nitrophenyl chloroformate, is a coupling agent used in the synthesis of ureas, carbamates, and carbonates. It is also used as a building block in solid-phase peptide synthesis (SPPS) to obtain altered

Description

General description

4-Nitrophenyl chloroformate, also known as p-nitrophenyl chloroformate, is a coupling agent used in the synthesis of ureas, carbamates, and carbonates. It is also used as a building block in solid-phase peptide synthesis (SPPS) to obtain altered side chain functionalities in peptides.

Application

4-Nitrophenyl chloroformate is used as:

  • A coupling agent to link the drug molecule with the polyrotaxane carrier molecule
  • As an activated ester reagent that enables the covalent coupling of a peptide onto a macromer, such as oligo(poly(ethylene glycol) fumarate) (OPF)

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Specifications
UPC:
41116134
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
100
Unit of Measurement:
GR
MPN:
160210-100G
CAS:
7693-46-1
Temperature Control Device:
Yes
Catalog No. C005B-078739
Price: $976.72
List Price: $1,085.24
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