Application
5, 15-DPP has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor:
- to analyze its effects on malignant peripheral nerve sheath tumor (MPNST) survival and proliferation
- to study its effects on the thymic stromal lymphopoietin (TSLP) modulation of nometastatic gene 23-H1 (NME1 or nm23-H1) expression in human trophoblasts
- to study its effects on 17β-estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced M2 polarization in human macrophages and endometrial stromal cells
Biochem/physiol Actions
5, 15-DPP is a selective STAT3 inhibitor and a selective STAT3-SH2 antagonist
- UPC:
- 41141905
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D4071-10MG