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Sigma-Aldrich

5 15-DPP (C005B-025812)

Application 5, 15-DPP has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor: to analyze its effects on malignant peripheral nerve sheath tumor (MPNST) survival and proliferation to study its effects on the

Description

Application

5, 15-DPP has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor:

  • to analyze its effects on malignant peripheral nerve sheath tumor (MPNST) survival and proliferation
  • to study its effects on the thymic stromal lymphopoietin (TSLP) modulation of nometastatic gene 23-H1 (NME1 or nm23-H1) expression in human trophoblasts
  • to study its effects on 17β-estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced M2 polarization in human macrophages and endometrial stromal cells

Biochem/physiol Actions

5, 15-DPP is a selective STAT3 inhibitor and a selective STAT3-SH2 antagonist

Specifications
UPC:
51112708
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
50
Unit of Measurement:
MG
MPN:
D4071-50MG
CAS:
22112-89-6
Controlled Substances and Cyanide:
Yes
Catalog No. C005B-025812
Price: $576.67
List Price: $640.74
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