6,7-Dimethoxycoumarin (C007B-137497)

Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation through activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells.An agent that can up-regulate the expression and activate CAR. Specification: 10mM in DMSO Molecular Formula: C11H10O4 Molecular Weight: 206.19 EC Number: 204-369-0 PubChem CID: 8417 Isomeric SMILES: COC1=C(C=C2C(=C1)C=CC(=O)O2)OC

UPC:

51183705

Condition:

New

Weight:

0.85 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

D420888-1ml

CAS:

120-08-1

Product Size:

1ml