8-PCPT-2'-O-ME-CAMP-AM (C005B-475075)

Catalog No.: C005B-475075
Mfr. No.: SML3072-1UMO
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: EA

Price: $776.51

List Price: $862.79

Biochem/physiol Actions 8-pCPT-2′:-O-Me-cAMP-AM (CPT-AM) is a membrane-permeant acetoxymethyl (AM) ester precusor form of the EPAC-selective cAMP analog (ESCA) 8-pCPT-2′:-O-Me-cAMP (CPT). CPT-AM is >:100-times more cell-permeable than

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Description
Specifications

Biochem/physiol Actions

8-pCPT-2′-O-Me-cAMP-AM (CPT-AM) is a membrane-permeant acetoxymethyl (AM) ester precusor form of the EPAC-selective cAMP analog (ESCA) 8-pCPT-2′-O-Me-cAMP (CPT). CPT-AM is >100-times more cell-permeable than CPT (by FRET using CFP-Epac-YFP-expressing A431; No effect by PKA FRET assay) and >100-times more efficient in stimulating cellular Rap1 activation (ECmax = 0.1 μM/CPT-AM vs. 100 μM/CPT; HUVECs).

UPC:: 51180000
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3072-1UMO
CAS:: 1152197-23-3

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