9Z,11E,13E-Octadecatrienoic Acid ethyl ester

A conjugated polyunsaturated fatty acid commonly found in plant seed oil which accounts for about 70% in tung oil and 60% of the total fatty acid composition of bitter gourd seed oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supplemented with α-ESA, apoptosis was induced via lipid peroxidation with an EC|50|of 20 μM. It also inhibits DNA polymerases and topoisomerases with IC|50|s ranging from ~5-20 μM for different isoforms of the enzymes. α-ESA ethyl ester is a neutral, more lipid soluble form of the free acid. Specification: 10mg/mL in ethanol Molecular Formula: C20H34O2 Molecular Weight: 306.48 PubChem CID: 12430060 Isomeric SMILES: CCCC/C=C/C=C/C=C/CCCCCCCC(=O)OCC Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/Z337626-SCI_346c749ccd691c25ab4d44664e850b89.pdf

UPC:

12352211

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

Z337626-10mg

CAS:

42021-86-3

Product Size:

10mg

Hazard Statement Codes:

H225:H350

Precautionary Statement Codes:

P201:P210:P202:P233:P240:P242:P243:P281