A-1-ANTITRYPSIN (POLYCLONAL) 1ML CONCENTRATE (C005B-098260)

General description

Alpha-1-Antitrypsin is a protease inhibitor from the serpin superfamily, which inhibits a number of protease enzymes from inflammatory cells. It is an acute-phase plasma protein predominantly produced in hepatocytes, although it is also made in enterocytes and some mononuclear white blood cells. Alpha-1-antitrypsin immunohistochemistry is used to detect the accumulation of alpha-1-antitrypsin in hepatic lesions and histiocytic tumors.
The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors, and yolk sac carcinomas. Positive staining for A-1-Antitrypsin may also be used in the detection of benign and malignant lesions of a histiocytic nature. The sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology.

Quality

IVD

IVD

IVD

RUO

Linkage

A-1-Antitrypsin Positive Control Slides , Product No. 223S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

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Other Notes

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Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

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UPC:

51111664

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

ML

MPN:

223A-16

Temperature Control Device:

Yes

Controlled Substances and Cyanide:

Yes