CAYMAN CHEMICAL
A 66-10 mg
A-66 is a potent, selective inhibitor of the PI3K isoform p110&alpha (IC50 = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110&alpha over other isoforms.
Description
A-66 is a potent, selective inhibitor of the PI3K isoform p110α (IC50 = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110α over other isoforms. A-66 is effective in vivo, suppressing the growth of SK-OV-3 tumor xenografts in mice. It also impairs all measures of in vivo insulin action in mice. A-66 partially suppresses B cell receptor-dependent Akt activation and proliferation.
Specifications
- UPC:
- 51183703
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 17382-10
- CAS:
- 1166227-08-2
Catalog No.
C003B-379840
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