A 841720 (C008B-240013)

A 841720 is a potent, non-competitive mGluR-1 antagonist that displays 34-fold selectivity over mGluR-5 (IC|50|values are 10 and 342 nM respectively). A 841720 displays no significant activity at a range of other GPCRs, ion channels and transporters. This compound also exhibits analgesic effects, decreases mechanical allodynia in models of neuropathic pain, and impairs cognitive function.

a potent & non-competitive mGluR-1 antagonist

Specifications & Purity: A 841720 is a potent, non-competitive mGluR-1 antagonist that displays 34-fold selectivity over mGluR-5 (IC|50|values are 10 and 342 nM respectively). A 841720 displays no significant activity at a range of other GPCRs, ion channels and transporters. This compound also exhibits analgesic effects, decreases mechanical allodynia in models of neuropathic pain, and impairs cognitive function.

Grade: Moligand™

Molecular Formula: C17H21N5OS

Molecular Weight: 343.45

PubChem CID: 11559235

Isomeric SMILES: CN(C)C1=C2C3=C(C(=O)N(C=N3)N4CCCCCC4)SC2=NC=C1

Storage Temperature: Protected from light;Store at -20°C;Argon charged

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A345272-SCI_c4b83858bd4d1714ac492110bdc065f7.pdf

UPC:

41115861

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A345272-1mg

Country of Origin:

China

CAS:

869802-58-4

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Precautionary Statement Codes:

P264