A1874 (C007B-021154)

Catalog No.: C007B-021154
Mfr. No.: A414180-10mg
Mfr. Name: Aladdin Scientific
Qty/UOM: 1
UOM: EA

Price: $806.23

List Price: $895.81

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Description
Specifications

InformationA1874 is a much improved nutlin-based, BRD4-degrading PROTAC and is able to degrade its target protein by 98% with nanomolar potency.TargetsBRD4In vitroIn HCT116 cells, A1874 causes a 97% decrease in viability and in A375 cells, A1874 causes a 98% loss of viability.A1874 reduced viability of Daudi cells by 70% and of MOLM-13 cells by 95%.Cell Research(from reference)Cell lines：HCT116 cell lines Concentrations：0-10 μM Incubation Time：24 h. Specification: 0.98 Molecular Formula: C58H62Cl3F2N9O7S Molecular Weight: 1173.59 PubChem CID: 124201003 Isomeric SMILES: CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCCNC(=O)C4=CC(=C(C=C4)NC(=O)[C@H]5[C@@H]([C@@]([C@@H](N5)CC(C)(C)C)(C#N)C6=C(C=C(C=C6)Cl)F)C7=C(C(=CC=C7)Cl)F)OC)C8=CC=C(C=C8)Cl)C

UPC:: 12352200
Condition:: New
Availability:: 2 weeks
Weight:: 1.06 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: A414180-10mg
CAS:: 2064292-12-0
Product Size:: 10mg

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