A22 hydrochloride

MreB Perturbing Compound A22 hydrochloride is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms.

Specifications & Purity: MreB Perturbing Compound A22 hydrochloride is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms.

Grade: Moligand™

Molecular Formula: C8H9Cl3N2S

Molecular Weight: 271.59

EC Number: 803-561-7

PubChem CID: 2830968

Isomeric SMILES: C1=CC(=C(C=C1CSC(=N)N)Cl)Cl.Cl

Storage Temperature: Protected from light;Store at -20°C;Argon charged;Desiccated

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A168784-SCI_830020dd54ac60753ca85a31a700459a.pdf

UPC:

51191573

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A168784-250mg

Country of Origin:

China

CAS:

22816-60-0

Product Size:

250mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H302

Precautionary Statement Codes:

P264;P270;P330;P301+P312;P501