Abemaciclib metabolite M2 (C007B-325826)

Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC 50 s of 1.2 and 1.3 nM, respectively. Anti-cancer activityIn VivoAbemaciclib metabolite M2 (LSN2839567) is bound to plasma proteins in rat, dog and human (83-92%), lower than Abemaciclib (95-99%). Abemaciclib metabolite M2 is the most prominent (active and major) plasma metabolites in human. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CDK4 1.2 nM (IC 50 ) CDK6 1.3 nM (IC 50 ). Specification: 0.99 Molecular Formula: C25H28F2N8 Molecular Weight: 478.54

UPC:

51111860

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A650455-5mg

CAS:

1231930-57-6

Product Size:

5mg