Sigma-Aldrich

ACETOPHENONE 99% (C005B-092329)

Name: ACETOPHENONE 99% (C005B-092329)
SKU: C005B-092329
Price: 187.32 USD
Availability: InStock

Acetophenone is an aromatic ketone used in the synthesis of alcohol by catalytic hydrogenation, and also in perfumery. Acetophenone (AP, methyl phenyl ketone) is a common industrial solvent.

Description

General description

Acetophenone is an aromatic ketone used in the synthesis of alcohol by catalytic hydrogenation, and also in perfumery.

Acetophenone (AP, methyl phenyl ketone) is a common industrial solvent. It can be synthesized from 1-phenylethanol in the presence of PdAu-NPs-TiO₂ (titanium dioxide-supported palladium gold bimetallic nanoparticles) hybrid. Its vacuum ultraviolet absorption spectrum shows absorption bands at 196, 191, 179 and 167mμ. AP reacts with α-naphtylphenylsilane in the presence of N-chelate ligands based on chiral oxazolines to undergo hydrosilylation with high enantioselectivity. It can also undergo hydrogenation reaction in the presence of different transition metal catalysts under different conditions.

Application

Acetophenone was used to induce peak currents in M71 neurons using voltage clamp. It may be used in the synthesis of N-(1-phenylethyl)formamide, via Leuckart reaction.