Sigma-Aldrich
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE FREE ACID (C005B-052085)
Application Adenosine 3′,5′-cyclic monophosphate has been used: as cell culture medium supplement in embryonic spinal neurons as a component of ringer solution for perfusion studies to induce neuroendocrine differentiation in human lung
Description
Application
Adenosine 3′,5′-cyclic monophosphate has been used:
- as cell culture medium supplement in embryonic spinal neurons
- as a component of ringer solution for perfusion studies
- to induce neuroendocrine differentiation in human lung cancer cell lines
Biochem/physiol Actions
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
Features and Benefits
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Specifications
- UPC:
- 12352204
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 5
- Unit of Measurement:
- GR
- MPN:
- A9501-5G
- CAS:
- 60-92-4
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