Adenosine receptor antagonist 2 (C007B-326025)

Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC 50 s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activityIn VivoAdenosine receptor antagonist 2 (compound L-1; po; 10, 30, 100 mg/kg; twice a day for 22 days) inhibits tumor growth in female C57BL / 6mice mice with MC38(#22)-hpd-L1 cells . Adenosine receptor antagonist 2 (iv; 2 mg/kg) has a CLz of 14.7 mL/min·kg and an AUC of 2252 h·ng/mL. Adenosine receptor antagonist 2 (po; 10 mg/kg) has a C max of 8730 ng/mL in adult male ICR mice (weight 25-40g) . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:A2a adenosine receptor 1 nM (IC 50 ) A2b adenosine receptor 3 nM (IC 50 ). Specification: 0.99 Molecular Formula: C23H21FN8O Molecular Weight: 444.46

UPC:

51181616

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A651145-10mg

CAS:

2703054-47-9

Product Size:

10mg