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CAYMAN CHEMICAL

AG-126-1 mg

A tyrphostin that is a poor inhibitor of EGFRK (IC50 = 450 &muM) and PDGFRK (IC50 > 100 &muM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 &muM blocks the production of TNF-&alpha,

Description
A tyrphostin that is a poor inhibitor of EGFRK (IC50 = 450 μM) and PDGFRK (IC50 > 100 μM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM; blocks the production of TNF-α, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response.
Specifications
UPC:
51112003
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
13297-1
CAS:
118409-62-4
Catalog No. C003B-360502
Price: $159.35
List Price: $177.05
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