AG-636 (C007B-021469)

InformationAG-636 AG-636 is an orally available inhibitor of dihydroorotate dehydrogenase (DHODH) with potential antineoplastic activity.TargetsDHODHIn vitroAG-636 reveals a strong enrichment in sensitivity to a novel dihydroorotate dehydrogenase (DHODH) in cancer cell lines of hematologic versus solid tumor origin.In vivoAG-636 results in robust tumor growth inhibition in xenograft lymphoma tumor models, with comparably poor activity in solid tumor models.Cell Research(from reference)Cell lines：Z138 cells, OCILY19 cells, JEKO1 cells, HCT116 cells, A549 cells Concentrations：10 μM Incubation Time：96 h. Specification: 10mM in DMSO Molecular Formula: C21H17N3O2 Molecular Weight: 343.38 PubChem CID: 77461001 Isomeric SMILES: CC1=CC=CC=C1C2=CC=C(C=C2)C3=CC(=C4C(=C3)N=NN4C)C(=O)O

UPC:

51111843

Condition:

New

Weight:

0.85 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A421973-1ml

CAS:

1623416-31-8

Product Size:

1ml