Almorexant (C008B-267657)

Almorexant (ACT 078573) is a potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.

Specifications & Purity: Almorexant (ACT 078573) is a potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.

Grade: Moligand™

Molecular Formula: C29H31F3N2O3

Molecular Weight: 512.56

PubChem CID: 23727689

Isomeric SMILES: CNC(=O)[C@@H](C1=CC=CC=C1)N2CCC3=CC(=C(C=C3[C@@H]2CCC4=CC=C(C=C4)C(F)(F)F)OC)OC

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51171518

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A607515-100mg

Country of Origin:

China

CAS:

871224-64-5

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H315;H319;H335

Precautionary Statement Codes:

P261;P264;P271;P280;P321;P302+P352;P304+P340;P305+P351+P338;P362+P364;P405;P403+P233;P501;P264+P265;P337+P317;P332+P317;P319