CAYMAN CHEMICAL

AMD 3465 (hydrobromide)-10 mg

Blocks the cell surface binding of the CXCR4 ligand CXCL12 (IC50 = 18 nM), inhibits calcium mobilization (IC50 = 4 nM), and (at 6,250 nM) completely blocks chemotaxis of SupT1 cells active against various HIV strains (IC50s = 6-12 nM).

Description

Blocks the cell surface binding of the CXCR4 ligand CXCL12 (IC50 = 18 nM), inhibits calcium mobilization (IC50 = 4 nM), and (at 6,250 nM) completely blocks chemotaxis of SupT1 cells active against various HIV strains (IC50s = 6-12 nM).

Specifications

UPC:

51111727

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

11959-10

CAS:

185991-07-5