AMG-47a

AMG-47a AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of interleukin-2 (IL-2) in mice.TargetsLCK (Cell-free assay) 3.4 μM

Src Inhibitors

Specifications & Purity: AMG-47a AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of interleukin-2 (IL-2) in mice.TargetsLCK (Cell-free assay) 3.4 μM

Molecular Formula: C29H28F3N5O2

Molecular Weight: 535.56

PubChem CID: 16086114

Isomeric SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51442708

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A412774-1mg

Country of Origin:

China

CAS:

882663-88-9

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90