AMN082 free base (C007B-018807)

AMN082 Dihydrochloride is a potent and selective agonist at mGluR-7, acting at an allosteric site. mGluR-7 is a metabotropic glutamate receptor 7. AMN082 has been shown to promote the proliferation and differentiation of neural progenitor cells.Product description：AMN082 free base, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 free base potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 free base shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects. Specification: 0.98 Molecular Formula: C28H28N2 Molecular Weight: 392.54 PubChem CID: 11698390 Isomeric SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A336629-SCI_026920ee2756addd86991c3a21a66048.pdf

UPC:

51292806

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No;ManufacturerName=Aladdin Scientific"

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A336629-25mg

CAS:

83027-13-8

Product Size:

25mg

Hazard Statement Codes:

H302:H400

Precautionary Statement Codes:

P264:P270:P273:P330:P391:P301+P312:P501

Controlled Substances and Cyanide:

Yes