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Sigma-Aldrich

ANTI-APC10 ANTIBODY (C005B-241026)

Anaphase-promoting complex subunit 10 (APC10) is a component of the anaphase promoting complex/cyclosome (APC/C) which mediates the ubiquitination and subsequent degradation of target proteins. The individual mRNA and protein levels of the APC/C

Description

General description

Anaphase-promoting complex subunit 10 (APC10) is a component of the anaphase promoting complex/cyclosome (APC/C) which mediates the ubiquitination and subsequent degradation of target proteins. The individual mRNA and protein levels of the APC/C are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

Immunogen

KLH-conjugated linear peptide corresponding to human APC10.

Application

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected APC10 in mouse heart tissue.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

This Anti-APC10 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of APC10.

Quality

Evaluated by Western Blotting in mouse heart tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected APC10 in 15 µg of mouse heart tissue lysate.

Target description

~21 kDa observed

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse heart tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse. species reactivity (predicted by homology): human (immunogen homology). technique(s): immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: Q9UM13. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... ANAPC10(10393). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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Specifications
UPC:
41181936
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
100
Unit of Measurement:
UG
MPN:
ABE608
Temperature Control Device:
Yes
Catalog No. C005B-241026
Price: $647.94
List Price: $719.94
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