General description
CXXC finger protein 1 (CFP1) is part of the Setd1A and Setd1B methyltransferase compounds. Research shows that CFP1 also interacts with the cytosine methylation mechanism. CFP1 is necessary for development of mammals and is a key regulator of chromatin structure. Embryonic stem cells that are missing CFP1 are more susceptible to DNA-damaging agents and tend to build up more DNA damage. CFP1 has been shown to also be a regulator of DNA repair.
Immunogen
GST-tagged recombinant protein corresponding to human CFP1.
Application
Use Anti-CFP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect CFP1 also known as CXXC finger 1 (PHD domain), cpG-binding protein.
Quality
Evaluated by Western Blot in HeLa nuclear extract.
Western Blot Analysis: 1:1,000 dilution of this antibody detected CFP1 on 10 µg of HeLa nuclear extract.
Target description
~78 kDa observed. A cross-reacting band observed at ~110 kDa
biological source: rabbit. Quality Level: 100. antibody form: serum. antibody product type: primary antibodies. clone: polyclonal. species reactivity: human, rat. technique(s): western blot: suitable. NCBI accession no.: NP_055408. UniProt accession no.: Q9P0U4. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... CXXC1(30827). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.- UPC:
- 12352203
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABE211
