Anti-mHUMMR Antibody (C15-1317-511)

General description

Hypoxia up-regulated mitochondrial movement regulator (HUMMR), a novel mitochondria protein, is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). HUMMR interacts with Miro-1 and Miro-2, mitochondrial proteins that are critical for mediating mitochondrial transport. Knockdown of HUMMR or HIF-1 function in neurons exposed to hypoxia markedly reduces mitochondrial content in axons.

Specificity

This antibody recognizes mouse HUMMR protein

Immunogen

Epitope: Unknown

Linear peptide corresponding to mouse HUMMR.

Application

Anti-mHUMMR Antibody is an antibody against mHUMMR for use in WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Quality

Evaluated by Western Blot in mouse testis lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected HUMMR on 10 µg of mouse testis lysate.

Target description

~ 45 kDa observed. 50 kDa calculated.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse testis lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse. technique(s): western blot: suitable. NCBI accession no.: NP_080634. UniProt accession no.: Q8VI64. shipped in: wet ice. target post-translational modification: unmodified. Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.