ANTI-PTRF (C005B-098853)

General description

Polymerase I and transcript release factor (PTRF) contains a leucine zipper motif, a nuclear localization signal, and PEST domains. It is critically involved in termination of transcription by stalling RNA poly I and releasing it from the elongating transcript. PTRF is also found localized to caveolae and regulates formation of the vesicles at the plasma membrane.

Immunogen

Synthetic peptide directed towards the middle region of mouse PTRF

Biochem/physiol Actions

In mouse, pausing of elongation complexes is mediated by the transcription termination factor TTF-I bound to the ′Sal box′ terminator downstream of the rDNA transcription unit. PTRF is a Pol I and transcript release factor for dissociation of paused ternary complexes.

Sequence

Synthetic peptide located within the following region: SEALPEKEGDELGEGERPEDDTAAIELSSDEAVEVEEVIEESRAERIKRS

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

UPC:

51262202

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

100

Unit of Measurement:

UL

MPN:

AV36965-100UL

Controlled Substances and Cyanide:

Yes