Aphidicolin (C007B-000671)

Aphidicolin is a tetracyclic diterpene antibiotic and DNA synthesis inhibitor isolated from Cephalosporium aphidicola. Aphidicolin is reported to specifically inhibit DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases. This compound blocks the cell cycle at early S phase and has been reported to be useful for synchronizing cell cycles in cultured eukaryotic cells. This compound is also noted to induce apoptosis in HeLa S3 cells after 18-24 hours of the cell cycle.A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes. Specification: 0.98 MDL Number: MFCD00083214 Molecular Formula: C20H34O4 Molecular Weight: 338.48 PubChem CID: 457964 Isomeric SMILES: C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O Beilstein Registry Number: 4689958 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A102398-SCI_119aa9b67f31b6dd475d8aea8731928d.pdf

UPC:

51284046

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A102398-5mg

CAS:

38966-21-1

Product Size:

5mg