Apoptolidin

Apoptolidin is a selective polyketide, apoptosis inducer produced by|Nocardiopsis|mainly inducing cell death in E1A-transformed cells and inhibiting the enzymatic activity of mitochondrial F|0|F|1|-ATPase. In addition, studies suggest that apoptolidin isomerizes in solution into isoapoptolidin within the time frame of most cell-based assays, however isoapoptolidin's ability to inhibit mitochondrial F|0|F|1|--ATPase is over 10 fold less effective. Furthermore, studies show that apoptolidin induced apoptosis can be inhibited by BCL-2. Specification: >95% Molecular Formula: C58H96O21 Molecular Weight: 1129.37 PubChem CID: 11297771 Isomeric SMILES: C[C@@H]1/C=C(/C=C(/C=C(/C(=O)O[C@@H](C[C@@H]([C@H](CC/C=C(/C=C/[C@H]1O[C@H]2[C@H]([C@@H]([C@H]([C@@H](O2)C)OC)O)O)/C)O)OC)[C@H]([C@]3([C@@H]([C@H]([C@H]([C@H](O3)C[C@H](COC)O[C@H]4C[C@]([C@H]([C@@H](O4)C)O[C@H]5C[C@H]([C@@H]([C@H](O5)C)O)OC)(C)O)C)O)C)O)O)/C)/C)/C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A329643-SCI_78d43183a2196f271f3b8f158746da50.pdf

UPC:

51111739

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A329643-100μg

CAS:

194874-06-1

Product Size:

100μg

Hazard Statement Codes:

H302:H315:H319

Precautionary Statement Codes:

P264:P270:P280