ARS-1323 (C008B-266714)

ARS-1323 is a KRAS G12C inhibitor. ARS-1323 specifically binds to the cysteine residue on the mutant K-Ras protein, locks it in the GDP-bound conformation, thereby blocking K-Ras activation and downstream signaling pathways. ARS-1323 can be used to investigate the signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.

Specifications & Purity: ARS-1323 is a KRAS G12C inhibitor. ARS-1323 specifically binds to the cysteine residue on the mutant K-Ras protein, locks it in the GDP-bound conformation, thereby blocking K-Ras activation and downstream signaling pathways. ARS-1323 can be used to investigate the signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.

Grade: Moligand™

Molecular Formula: C21H17ClF2N4O2

Molecular Weight: 430.84

PubChem CID: 137003167

Isomeric SMILES: C=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)F

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51442417

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A650031-25mg

Country of Origin:

China

CAS:

1698024-73-5

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90