Sigma-Aldrich
AVN-944 (C005B-308987)
Biochem/physiol Actions AVN-944 is an orally bioavailable, highly selective, nonnucleoside and uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with antitumor and antiviral activities. AVN-944 depletes intracellular GMP levels
Description
Biochem/physiol Actions
AVN-944 is an orally bioavailable, highly selective, nonnucleoside and uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with antitumor and antiviral activities. AVN-944 depletes intracellular GMP levels and inhibits DNA and RNA viruses replication via reduction of GTP pools in infected cells. Arrests a wide range of hematologic and epithelial tumor cell types proliferation (IC50 of 0.02 µM to 0.279 µM).
Specifications
- UPC:
- 51111870
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SML3440-5MG
- CAS:
- 297730-17-7
Catalog No.
C005B-308987
-
Fast shipping — 3-day lead time
-
Guaranteed quality & reliable delivery
-
Shipping Lead-Time: 3-5 Days
